{"id":186489,"date":"2024-03-31T12:27:56","date_gmt":"2024-03-31T17:27:56","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/03\/researchers-discover-key-metabolic-process-responsible-for-rapid-immune-responses"},"modified":"2024-03-31T12:27:56","modified_gmt":"2024-03-31T17:27:56","slug":"researchers-discover-key-metabolic-process-responsible-for-rapid-immune-responses","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/03\/researchers-discover-key-metabolic-process-responsible-for-rapid-immune-responses","title":{"rendered":"Researchers Discover Key Metabolic Process Responsible for Rapid Immune Responses"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researchers-discover-key-metabolic-process-responsible-for-rapid-immune-responses.jpg\"><\/a><\/p>\n<p>Researchers from Children\u2019s Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells.<\/p>\n<p>The findings also indicate that a better understanding of this metabolite and its role in immune response could improve the design of immunotherapies and create longer-lived responses against different types of cancer as well as enhance vaccine strategies. The findings were published online by the journal Science Immunology in a paper titled \u201cSingle-cell NAD(H) levels predict clonal lymphocyte expansion dynamics.\u201d<\/p>\n<p>Antigens are foreign substances that our immune system recognizes and responds to by producing more T and B cells. These cells each have unique receptors that recognize specific antigens and can respond appropriately, and they can \u201cremember\u201d and respond similarly when exposed to the same antigen again.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from Children\u2019s Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells. The findings also indicate that a better understanding of this metabolite [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-186489","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186489","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=186489"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186489\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=186489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=186489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=186489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}