{"id":186315,"date":"2024-03-29T16:24:54","date_gmt":"2024-03-29T21:24:54","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/03\/fine-tuning-of-cpg-spatial-distribution-with-dna-origami-for-improved-cancer-vaccination"},"modified":"2024-03-29T16:24:54","modified_gmt":"2024-03-29T21:24:54","slug":"fine-tuning-of-cpg-spatial-distribution-with-dna-origami-for-improved-cancer-vaccination","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/03\/fine-tuning-of-cpg-spatial-distribution-with-dna-origami-for-improved-cancer-vaccination","title":{"rendered":"Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/fine-tuning-of-cpg-spatial-distribution-with-dna-origami-for-improved-cancer-vaccination2.jpg\"><\/a><\/p>\n<p>Congratulations to Yang (Claire) Zeng and her team for their work on DoriVac, a DNA origami vaccine which utilizes precisely spaced CpG oligonucleotides to enhance immunological responses against chosen antigens.<\/p>\n<hr>\n<p>The spacing of ligands presented to cells can have a huge impact on cellular responses. DNA origami is used to block structures to control the distribution of Toll-like receptor ligands and optimize presentation in the activation of dendritic cells in cancer immunotherapy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to Yang (Claire) Zeng and her team for their work on DoriVac, a DNA origami vaccine which utilizes precisely spaced CpG oligonucleotides to enhance immunological responses against chosen antigens. The spacing of ligands presented to cells can have a huge impact on cellular responses. DNA origami is used to block structures to control the [\u2026]<\/p>\n","protected":false},"author":636,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-186315","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186315","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/636"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=186315"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186315\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=186315"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=186315"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=186315"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}