{"id":185523,"date":"2024-03-20T10:22:25","date_gmt":"2024-03-20T15:22:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/03\/world-first-trial-of-regenerative-hearing-drug-is-successfully-completed"},"modified":"2024-03-20T10:22:25","modified_gmt":"2024-03-20T15:22:25","slug":"world-first-trial-of-regenerative-hearing-drug-is-successfully-completed","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/03\/world-first-trial-of-regenerative-hearing-drug-is-successfully-completed","title":{"rendered":"World-first Trial of Regenerative Hearing Drug is Successfully Completed"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/world-first-trial-of-regenerative-hearing-drug-is-successfully-completed2.jpg\"><\/a><\/p>\n<p>Researchers at UCL and UCLH have successfully completed the first trial of a therapy designed to restore hearing loss. The REGAIN trial, the results of which were published in Nature Communications, was the first study of a treatment aimed at restoring lost hearing, focusing on a drug with the technical name gamma-secretase inhibitor LY3056480.<\/p>\n<p>The researchers found that while the therapy did not restore hearing across the group of adults with mild to moderate hearing loss, a deeper analysis of the data showed changes in various hearing tests in some patients, suggesting the drug has some activity in the inner ear.<\/p>\n<p>These so-called efficacy signals call for further development of LY3056480\u2014using the learnings from this trial.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at UCL and UCLH have successfully completed the first trial of a therapy designed to restore hearing loss. The REGAIN trial, the results of which were published in Nature Communications, was the first study of a treatment aimed at restoring lost hearing, focusing on a drug with the technical name gamma-secretase inhibitor LY3056480. The [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-185523","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/185523","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=185523"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/185523\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=185523"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=185523"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=185523"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}