{"id":185348,"date":"2024-03-18T16:22:57","date_gmt":"2024-03-18T21:22:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/03\/intermittent-food-intake-activates-a-gps-gene-in-liver-cells-thus-completing-the-development-of-the-liver-after-birth"},"modified":"2024-03-18T16:22:57","modified_gmt":"2024-03-18T21:22:57","slug":"intermittent-food-intake-activates-a-gps-gene-in-liver-cells-thus-completing-the-development-of-the-liver-after-birth","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/03\/intermittent-food-intake-activates-a-gps-gene-in-liver-cells-thus-completing-the-development-of-the-liver-after-birth","title":{"rendered":"Intermittent food intake activates a \u2018GPS gene\u2019 in liver cells, thus completing the development of the liver after birth"},"content":{"rendered":"<p><a class=\"blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/intermittent-food-intake-activates-a-gps-gene-in-liver-cells-thus-completing-the-development-of-the-liver-after-birth.jpg\"><\/a><\/p>\n<p>Until now, it was not clear how hepatocytes were assigned tasks related to their localization. Researchers at the Spanish National Cancer Research Center (CNIO) have discovered that a gene, mTOR, is responsible for organizing the hepatocyte <em>position map<\/em>.<\/p>\n<p>They also found that what triggers hepatocyte specialization is feeding after birth. The difference is marked by how nutrients reach the organism before and after birth: with no interruptions through the umbilical cord in one case, or in an intermittent fashion \u2013when eating\u2013 in the other. The alternation of periods with and without available nutrients activates the mTOR gene and causes the hepatocytes to specialize, which completes the maturation of the liver.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Until now, it was not clear how hepatocytes were assigned tasks related to their localization. Researchers at the Spanish National Cancer Research Center (CNIO) have discovered that a gene, mTOR, is responsible for organizing the hepatocyte position map. They also found that what triggers hepatocyte specialization is feeding after birth. The difference is marked by [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1506],"tags":[],"class_list":["post-185348","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-food"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/185348","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=185348"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/185348\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=185348"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=185348"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=185348"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}