{"id":185092,"date":"2024-03-14T14:23:46","date_gmt":"2024-03-14T19:23:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/03\/motixafortide-and-stem-cell-transplants-for-multiple-myeloma"},"modified":"2024-03-14T14:23:46","modified_gmt":"2024-03-14T19:23:46","slug":"motixafortide-and-stem-cell-transplants-for-multiple-myeloma","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/03\/motixafortide-and-stem-cell-transplants-for-multiple-myeloma","title":{"rendered":"Motixafortide and Stem Cell Transplants for Multiple Myeloma"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/motixafortide-and-stem-cell-transplants-for-multiple-myeloma2.jpg\"><\/a><\/p>\n<p>The recently approved drug motixafortide may help improve stem cell transplants for people with multiple myeloma. Learn more about this treatment:<\/p>\n<hr>\n<p>However, Dr. Schulz cautioned, this finding is not definitive because the two drugs were not tested head-to-head in a randomized trial. A randomized clinical trial comparing the drugs \u201cwould have been a better and fairer comparison,\u201d he said, since plerixafor and motixafortide both work by blocking a chemical signal that tells stem cells to stay in the bone marrow.<\/p>\n<p>Finally, Dr. Crees and his colleagues did a series of experiments looking at the different types of blood-forming stem cells mobilized by G-CSF plus placebo, motixafortide, or plerixafor.<\/p>\n<p>\u201cNot all stem cells are equal,\u201d Dr. Schulz explained. And these experiments showed that motixafortide mobilized a higher percentage than plerixafor or placebo of the most primitive types of blood-forming stem cells, which could potentially lead to faster engraftment, he said.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The recently approved drug motixafortide may help improve stem cell transplants for people with multiple myeloma. Learn more about this treatment: However, Dr. Schulz cautioned, this finding is not definitive because the two drugs were not tested head-to-head in a randomized trial. A randomized clinical trial comparing the drugs \u201cwould have been a better and [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19],"tags":[],"class_list":["post-185092","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/185092","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=185092"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/185092\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=185092"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=185092"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=185092"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}