{"id":184458,"date":"2024-03-09T00:15:00","date_gmt":"2024-03-09T06:15:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/03\/first-uk-patients-receive-experimental-mrna-therapy-for-cancer"},"modified":"2024-03-09T00:15:00","modified_gmt":"2024-03-09T06:15:00","slug":"first-uk-patients-receive-experimental-mrna-therapy-for-cancer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/03\/first-uk-patients-receive-experimental-mrna-therapy-for-cancer","title":{"rendered":"First UK patients receive experimental mRNA therapy for cancer"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/first-uk-patients-receive-experimental-mrna-therapy-for-cancer.jpg\"><\/a><\/p>\n<p>The first UK patients received the experimental mRNA therapy \u2013 a type of immunotherapy treatment called mRNA-4359 \u2013 at Imperial College Healthcare NHS Trust as part of a phase 1\/2 clinical trial. The trial aims to evaluate its safety and potential for treating melanoma, lung cancer and other \u2018solid tumour\u2019 cancers.<\/p>\n<p>The treatment is designed using messenger RNA (mRNA) and works by presenting common markers of tumours to the patient\u2019s immune system. This should help to train patients\u2019 immune systems to recognise and fight cancer cells expressing these markers, but also potentially eliminate cells that may suppress the immune response.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The first UK patients received the experimental mRNA therapy \u2013 a type of immunotherapy treatment called mRNA-4359 \u2013 at Imperial College Healthcare NHS Trust as part of a phase 1\/2 clinical trial. The trial aims to evaluate its safety and potential for treating melanoma, lung cancer and other \u2018solid tumour\u2019 cancers. The treatment is designed [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-184458","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/184458","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=184458"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/184458\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=184458"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=184458"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=184458"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}