{"id":184035,"date":"2024-02-29T23:26:43","date_gmt":"2024-03-01T05:26:43","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/02\/qa-how-a-potential-treatment-for-alzheimers-disease-could-also-work-for-type-2-diabetes"},"modified":"2024-02-29T23:26:43","modified_gmt":"2024-03-01T05:26:43","slug":"qa-how-a-potential-treatment-for-alzheimers-disease-could-also-work-for-type-2-diabetes","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/02\/qa-how-a-potential-treatment-for-alzheimers-disease-could-also-work-for-type-2-diabetes","title":{"rendered":"Q&amp;A: How a potential treatment for Alzheimer\u2019s disease could also work for type 2 diabetes"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/qa-how-a-potential-treatment-for-alzheimers-disease-could-also-work-for-type-2-diabetes3.jpg\"><\/a><\/p>\n<p>Of the 38 million Americans who have diabetes, at least 90% have type 2, according to the Centers for Disease Control and Prevention. Type 2 diabetes occurs over time and is characterized by a loss of the cells in the pancreas that make the hormone insulin, which helps the body manage sugar.<\/p>\n<p>These cells make another protein, called islet amyloid polypeptide or IAPP, which has been found clumped together in many type 2 diabetes patients. The formation of IAPP clusters is comparable to how a protein in the brains of Alzheimer\u2019s disease patients sticks together to eventually form the signature plaques associated with that disease.<\/p>\n<p>Researchers at the University of Washington have demonstrated more similarities between IAPP clusters and those in Alzheimer\u2019s. The team <a href=\"https:\/\/medicalxpress.com\/news\/2019-04-synthetic-peptide-inhibit-toxicity-aggregation.html\">previously showed<\/a> that a <a href=\"https:\/\/medicalxpress.com\/tags\/synthetic+peptide\/\" rel=\"tag\" class=\"\">synthetic peptide<\/a> can block the formation of small, toxic Alzheimer\u2019s protein clusters. Now, in a <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/pro.4854\">recently published paper<\/a> in <i><i>Protein Science<\/i>,<\/i> the researchers have used a similar peptide to block the formation of IAPP clusters.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Of the 38 million Americans who have diabetes, at least 90% have type 2, according to the Centers for Disease Control and Prevention. Type 2 diabetes occurs over time and is characterized by a loss of the cells in the pancreas that make the hormone insulin, which helps the body manage sugar. These cells make [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-184035","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/184035","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=184035"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/184035\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=184035"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=184035"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=184035"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}