{"id":183914,"date":"2024-02-28T15:28:27","date_gmt":"2024-02-28T21:28:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/02\/how-early-stage-cancer-cells-hide-from-the-immune-system"},"modified":"2024-02-28T15:28:27","modified_gmt":"2024-02-28T21:28:27","slug":"how-early-stage-cancer-cells-hide-from-the-immune-system","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/02\/how-early-stage-cancer-cells-hide-from-the-immune-system","title":{"rendered":"How early-stage cancer cells hide from the immune system"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/how-early-stage-cancer-cells-hide-from-the-immune-system.jpg\"><\/a><\/p>\n<p>One of the immune system\u2019s primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors.<\/p>\n<p>A new study from MIT and Dana-Farber Cancer Institute has identified one strategy that helps these <a href=\"https:\/\/medicalxpress.com\/tags\/precancerous+cells\/\" rel=\"tag\" class=\"\">precancerous cells<\/a> avoid immune detection. The researchers found that early in colon cancer development, cells that turn on a gene called SOX17 can become essentially invisible to the immune system.<\/p>\n<p>If scientists could find a way to block SOX17 function or the pathway that it activates, this may offer a new way to treat early-stage cancers before they grow into larger tumors, the researchers say.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>One of the immune system\u2019s primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors. A new study from MIT and Dana-Farber Cancer Institute has identified one strategy that helps these precancerous cells avoid immune detection. [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-183914","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/183914","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=183914"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/183914\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=183914"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=183914"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=183914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}