{"id":182535,"date":"2024-02-12T09:24:02","date_gmt":"2024-02-12T15:24:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/02\/how-obesity-dismantles-our-mitochondria-study-reveals-key-mechanism-behind-obesity-related-metabolic-dysfunction"},"modified":"2024-02-12T09:24:02","modified_gmt":"2024-02-12T15:24:02","slug":"how-obesity-dismantles-our-mitochondria-study-reveals-key-mechanism-behind-obesity-related-metabolic-dysfunction","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/02\/how-obesity-dismantles-our-mitochondria-study-reveals-key-mechanism-behind-obesity-related-metabolic-dysfunction","title":{"rendered":"How Obesity Dismantles our Mitochondria: Study reveals Key Mechanism behind Obesity-related Metabolic Dysfunction"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/how-obesity-dismantles-our-mitochondria-study-reveals-key-mechanism-behind-obesity-related-metabolic-dysfunction2.jpg\"><\/a><\/p>\n<p>The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.<\/p>\n<p>Now, researchers from University of California San Diego School of Medicine have shed new light on how obesity affects our mitochondria, the all-important energy-producing structures of our cells.<\/p>\n<p>In a study published in Nature Metabolism, the researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart into smaller mitochondria with reduced capacity for burning fat. Further, they discovered that this process is controlled by a single gene. By deleting this gene from the mice, they were able to protect them from excess weight gain, even when they ate the same high-fat diet as other mice.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities. Now, researchers from University of California San Diego [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-182535","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/182535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=182535"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/182535\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=182535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=182535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=182535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}