{"id":182371,"date":"2024-02-09T11:27:52","date_gmt":"2024-02-09T17:27:52","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/02\/pioneering-technique-reveals-new-layer-of-human-gene-regulation"},"modified":"2024-02-09T11:27:52","modified_gmt":"2024-02-09T17:27:52","slug":"pioneering-technique-reveals-new-layer-of-human-gene-regulation","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/02\/pioneering-technique-reveals-new-layer-of-human-gene-regulation","title":{"rendered":"Pioneering technique reveals new layer of human gene regulation"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/pioneering-technique-reveals-new-layer-of-human-gene-regulation2.jpg\"><\/a><\/p>\n<p>A technique can determine for the first time how frequently, and exactly where, a molecular event called \u201cbacktracking\u201d occurs throughout the genetic material (genome) of any species, a new study shows.<\/p>\n<p>Published online February 9 in <i><i>Molecular Cell<\/i>,<\/i> the <a href=\"https:\/\/www.cell.com\/molecular-cell\/fulltext\/S1097-2765(24)00055-8\">study<\/a> results support the theory that backtracking represents a widespread form of gene regulation, which influences thousands of <a href=\"https:\/\/phys.org\/tags\/human+genes\/\" rel=\"tag\" class=\"\">human genes<\/a>, including many involved in basic life processes like <a href=\"https:\/\/phys.org\/tags\/cell+division\/\" rel=\"tag\" class=\"\">cell division<\/a> and development in the womb.<\/p>\n<p>Led by researchers from NYU Grossman School of Medicine, the work revolves around genes, the stretches of DNA molecular \u201cletters\u201d arranged in a certain order (sequence) to encode the blueprints for most organisms. In both humans and bacteria, the first step in a gene\u2019s expression, transcription, proceeds as a protein \u201cmachine\u201d called RNA polymerase II ticks down the DNA chain, reading genetic instructions in one direction.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A technique can determine for the first time how frequently, and exactly where, a molecular event called \u201cbacktracking\u201d occurs throughout the genetic material (genome) of any species, a new study shows. Published online February 9 in Molecular Cell, the study results support the theory that backtracking represents a widespread form of gene regulation, which influences [\u2026]<\/p>\n","protected":false},"author":367,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-182371","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/182371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/367"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=182371"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/182371\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=182371"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=182371"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=182371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}