{"id":181306,"date":"2024-01-24T14:25:12","date_gmt":"2024-01-24T20:25:12","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/01\/recent-advances-in-the-evolution-of-aging-and-lifespan"},"modified":"2024-01-24T14:25:12","modified_gmt":"2024-01-24T20:25:12","slug":"recent-advances-in-the-evolution-of-aging-and-lifespan","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/01\/recent-advances-in-the-evolution-of-aging-and-lifespan","title":{"rendered":"Recent advances in the evolution of aging and lifespan"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/recent-advances-in-the-evolution-of-aging-and-lifespan2.jpg\"><\/a><\/p>\n<p>Aging is a common phenomenon among organisms, however, lifespan tends to vary across different species to a significant extent among vertebrates themselves. Aging occurs due to the gradual increase in DNA damage, disruption of cellular organelles, deregulation of protein function, disrupted metabolism and oxidative stress [<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/B9780123914989000085\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a>].<\/p>\n<p><strong><em>Longevity. Technology: The differences in lifespan are driven by trade-offs and evolutionary trajectories in the genomes of organisms. Age-specific selection also impacts allele (variations of a gene) frequencies in a population. This in turn impacts environment-specific mortality risk and disease susceptibility. Moreover, mutational processes are influenced by life history and age in both somatic and germline cells.<\/em><\/strong><\/p>\n<p><strong><em>Now, a new review published in <\/em>Trends in Genetics<em> discusses recent advances in the evolution of aging at population, organismal and cellular scales.<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Aging is a common phenomenon among organisms, however, lifespan tends to vary across different species to a significant extent among vertebrates themselves. Aging occurs due to the gradual increase in DNA damage, disruption of cellular organelles, deregulation of protein function, disrupted metabolism and oxidative stress [1]. Longevity. Technology: The differences in lifespan are driven by [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,385,412,269],"tags":[],"class_list":["post-181306","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-evolution","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/181306","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=181306"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/181306\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=181306"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=181306"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=181306"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}