{"id":18087,"date":"2015-10-03T01:42:16","date_gmt":"2015-10-03T08:42:16","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2015\/10\/how-do-brain-stem-cells-age-their-damage-filter-breaks-down"},"modified":"2017-06-04T11:34:39","modified_gmt":"2017-06-04T18:34:39","slug":"how-do-brain-stem-cells-age-their-damage-filter-breaks-down","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2015\/10\/how-do-brain-stem-cells-age-their-damage-filter-breaks-down","title":{"rendered":"How Do Brain Stem Cells Age? Their Damage Filter Breaks Down"},"content":{"rendered":"<p><a class=\\'blog-photo\\' href=\"https:\/\/lifeboat.com\/blog.images\/how-do-brain-stem-cells-age-their-damage-filter-breaks-down.jpg\"><\/a><\/p>\n<p>Could discovering how neural stem cells protect themselves from damage lead to treatment that helps combat aging?<\/p>\n<p>We now know that stem cells in the brain do in fact divide, and that this regenerative capacity begins to falter with age. The majority of our cells don\u2019t divide, and the bulk of division falls to stem cell niches dotted across our body. Stem cell populations do age, but they\u2019re more resistant than \u2018normal\u2019 cells are, and they produce higher levels of telomerase \u2014 enabling them to divide for years.<\/p>\n<p><strong>How do brain stem cells remain free of damage?<\/strong><\/p>\n<p>Neural stem cells aren\u2019t perfectly protected from aging, but they\u2019re generally a hardier bunch. Scientists from the University of Zurich have now discovered that part of this aging resistance in neural stem cells is due to a \u2018<strong>diffusion barrier<\/strong>\u2019. When they divide, these cells produce a barrier which filters out damaged proteins to one side, allowing the new cell to be damage-free.<\/p>\n<p><a href=\"http:\/\/www.longevityreporter.org\/blog\/2015\/9\/21\/how-do-the-brains-stem-cells-avoid-damage\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Could discovering how neural stem cells protect themselves from damage lead to treatment that helps combat aging? We now know that stem cells in the brain do in fact divide, and that this regenerative capacity begins to falter with age. The majority of our cells don\u2019t divide, and the bulk of division falls to stem [\u2026]<\/p>\n","protected":false},"author":386,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-18087","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/18087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/386"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=18087"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/18087\/revisions"}],"predecessor-version":[{"id":64021,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/18087\/revisions\/64021"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=18087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=18087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=18087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}