{"id":180821,"date":"2024-01-18T20:27:57","date_gmt":"2024-01-19T02:27:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/01\/toxic-rnas-the-hidden-cause-of-neuron-death-in-alzheimers-uncovered"},"modified":"2024-01-18T20:27:57","modified_gmt":"2024-01-19T02:27:57","slug":"toxic-rnas-the-hidden-cause-of-neuron-death-in-alzheimers-uncovered","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/01\/toxic-rnas-the-hidden-cause-of-neuron-death-in-alzheimers-uncovered","title":{"rendered":"Toxic RNAs: The Hidden Cause of Neuron Death in Alzheimer\u2019s Uncovered"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/toxic-rnas-the-hidden-cause-of-neuron-death-in-alzheimers-uncovered3.jpg\"><\/a><\/p>\n<p>A new Northwestern Medicine study shows that RNA interference may play a key role in Alzheimer\u2019s. For the first time, scientists have identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer\u2019s and aged brains. Short strands of protective RNAs are decreased during aging, the scientists report, which may allow Alzheimer\u2019s to develop.<\/p>\n<p>The study also found that older individuals with a superior memory capacity (known as SuperAgers) have higher amounts of protective short RNA strands in their brain cells. SuperAgers are individuals aged 80 and older with a memory capacity of individuals 20 to 30 years younger.<\/p>\n<p>\u201cNobody has ever connected the activities of RNAs to Alzheimer\u2019s,\u201d said corresponding study author Marcus Peter, the Tom D. Spies Professor of Cancer Metabolism at Northwestern University Feinberg School of Medicine. \u201cWe found that in aging brain cells, the balance between toxic and protective sRNAs shifts toward toxic ones.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new Northwestern Medicine study shows that RNA interference may play a key role in Alzheimer\u2019s. For the first time, scientists have identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer\u2019s and aged brains. Short strands of protective RNAs are decreased during aging, the scientists report, which [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-180821","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180821","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=180821"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180821\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=180821"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=180821"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=180821"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}