{"id":180552,"date":"2024-01-15T15:22:47","date_gmt":"2024-01-15T21:22:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/01\/novel-regulator-of-immune-evasion-in-cancer-identified"},"modified":"2024-01-15T15:22:47","modified_gmt":"2024-01-15T21:22:47","slug":"novel-regulator-of-immune-evasion-in-cancer-identified","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/01\/novel-regulator-of-immune-evasion-in-cancer-identified","title":{"rendered":"Novel regulator of immune evasion in cancer identified"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/novel-regulator-of-immune-evasion-in-cancer-identified3.jpg\"><\/a><\/p>\n<p>Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies, according to recent findings <a href=\"https:\/\/www.jci.org\/articles\/view\/167728\">published<\/a> in the Journal of Clinical Investigation.<\/p>\n<p>\u201cThe study provides a molecular insight into understanding why some <a href=\"https:\/\/medicalxpress.com\/tags\/cancer+patients\/\" rel=\"tag\" class=\"\">cancer patients<\/a> cannot be treated by the checkpoint blockade antitumor therapy, but others can,\u201d said Deyu Fang, Ph.D., the Hosmer Allen Johnson Professor of Pathology and senior author of the study.<\/p>\n<p>Antitumor immunotherapy is a type of <a href=\"https:\/\/medicalxpress.com\/tags\/cancer\/\" rel=\"tag\" class=\"\">cancer<\/a> treatment that helps the immune system in fighting cancer and includes a range of therapy types, such as <a href=\"https:\/\/medicalxpress.com\/tags\/immune+checkpoint+inhibitors\/\" rel=\"tag\" class=\"\">immune checkpoint inhibitors<\/a>. Immune checkpoints help prevent the immune system from being too strong and eradicating other <a href=\"https:\/\/medicalxpress.com\/tags\/cells\/\" rel=\"tag\" class=\"\">cells<\/a>, including <a href=\"https:\/\/medicalxpress.com\/tags\/cancer+cells\/\" rel=\"tag\" class=\"\">cancer cells<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies, according to recent findings published in the Journal of Clinical Investigation. \u201cThe study provides a molecular insight into understanding why some cancer patients cannot be treated by the checkpoint blockade [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,20],"tags":[],"class_list":["post-180552","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180552","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=180552"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180552\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=180552"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=180552"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=180552"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}