{"id":180335,"date":"2024-01-12T15:23:37","date_gmt":"2024-01-12T21:23:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/01\/going-beyond-b-cells-in-the-search-for-a-more-multi-targeted-vaccine"},"modified":"2024-01-12T15:23:37","modified_gmt":"2024-01-12T21:23:37","slug":"going-beyond-b-cells-in-the-search-for-a-more-multi-targeted-vaccine","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/01\/going-beyond-b-cells-in-the-search-for-a-more-multi-targeted-vaccine","title":{"rendered":"Going beyond B cells in the search for a more multi-targeted vaccine"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/going-beyond-b-cells-in-the-search-for-a-more-multi-targeted-vaccine2.jpg\"><\/a><\/p>\n<p><strong><em>Part 3:<\/em><\/strong><em> This is the last of a three-part series on how Stanford Medicine researchers are designing vaccines that protect people from not merely individual viral strains but broad ranges of them. The ultimate goal: a vaccine with coverage so broad it can protect against viruses never before encountered.<\/em><\/p>\n<p>Until now, vaccine efforts have mainly focused on stimulating B cells, described and discussed in <a href=\"https:\/\/scopeblog.stanford.edu\/2024\/01\/08\/better-vaccine-multiple-strains-closer-to-universal\/\">Part 1<\/a> and <a href=\"https:\/\/scopeblog.stanford.edu\/2024\/01\/10\/searching-for-vaccine-variability-in-the-land-of-the-flu\/\">Part 2<\/a>. These antibody-producing immune cells\u2019 virtue of being highly specific in what they target is also a vice. An antibody against influenza is unlikely to ever bind to, say, a coronavirus or a rabies virus.<\/p>\n<p>Even when a virus mutates in some small way that distorts or disguises one of its biochemical bull\u2019s-eyes, antibodies that worked before (because they aimed at that particular bull\u2019s-eye) are now unemployed.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Part 3: This is the last of a three-part series on how Stanford Medicine researchers are designing vaccines that protect people from not merely individual viral strains but broad ranges of them. The ultimate goal: a vaccine with coverage so broad it can protect against viruses never before encountered. Until now, vaccine efforts have mainly [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19],"tags":[],"class_list":["post-180335","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180335","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=180335"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180335\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=180335"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=180335"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=180335"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}