{"id":180216,"date":"2024-01-10T19:22:25","date_gmt":"2024-01-11T01:22:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/01\/breakthrough-in-gene-editing-enhanced-virus-like-particles-promise-new-era-in-genetic-disease-treatment"},"modified":"2024-01-10T19:22:25","modified_gmt":"2024-01-11T01:22:25","slug":"breakthrough-in-gene-editing-enhanced-virus-like-particles-promise-new-era-in-genetic-disease-treatment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/01\/breakthrough-in-gene-editing-enhanced-virus-like-particles-promise-new-era-in-genetic-disease-treatment","title":{"rendered":"Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/breakthrough-in-gene-editing-enhanced-virus-like-particles-promise-new-era-in-genetic-disease-treatment2.jpg\"><\/a><\/p>\n<p><b>Background: The Promise of Prime Editing<\/b><\/p>\n<p>Prime editing is a promising technology for changing genomic deoxyribonucleic acid (DNA) that has the potential to be used to cure genetic diseases in individuals. Prime editors are proteins that can replace a specific deoxyribonucleic acid sequence with another. PE systems necessitate three distinct <a href=\"https:\/\/www.news-medical.net\/life-sciences\/What-is-Nucleic-Acid.aspx\" class=\"\">nucleic acid<\/a> hybridizations and are not dependent on double-strand deoxyribonucleic acid breaks or donor deoxyribonucleic acid templates.<\/p>\n<p>Researchers must devise efficient and safe techniques to deliver prime editors in tissues in the <em>in vivo<\/em> settings to fulfill PE\u2019s objective. While viral delivery techniques such as adenoviruses and adeno-associated viruses (AAVs) can transport PE <em>in vivo<\/em>, non-viral delivery techniques like lipid nanoparticles can sidestep these concerns by packaging PEs as temporarily expressing messenger ribonucleic acids.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background: The Promise of Prime Editing Prime editing is a promising technology for changing genomic deoxyribonucleic acid (DNA) that has the potential to be used to cure genetic diseases in individuals. Prime editors are proteins that can replace a specific deoxyribonucleic acid sequence with another. PE systems necessitate three distinct nucleic acid hybridizations and are [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412,4],"tags":[],"class_list":["post-180216","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=180216"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/180216\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=180216"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=180216"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=180216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}