{"id":179886,"date":"2024-01-05T10:24:20","date_gmt":"2024-01-05T16:24:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/01\/new-discovery-could-aid-regenerative-heart-therapies"},"modified":"2024-01-05T10:24:20","modified_gmt":"2024-01-05T16:24:20","slug":"new-discovery-could-aid-regenerative-heart-therapies","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/01\/new-discovery-could-aid-regenerative-heart-therapies","title":{"rendered":"New Discovery could Aid Regenerative Heart Therapies"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-discovery-could-aid-regenerative-heart-therapies3.jpg\"><\/a><\/p>\n<p>Researchers identify RBFox1 as a key intrinsic regulator of heart muscle cell maturation, overcoming a major limitation in cardiac regenerative therapy and disease modelling and demonstrating for the first time that RNA splicing control can significantly impact this process.<\/p>\n<p>Scientists led by Duke-NUS Medical School in Singapore and the University of California, Los Angeles, (UCLA) in the United States have discovered a new control mechanism that can drive the maturation of human stem cell-derived heart muscle cells, providing fresh insight into the maturation process of heart muscle cells from fetal to adult form.<\/p>\n<p>After birth, heart muscle cells undergo extensive changes to become fully mature adult cells, altering their form, function and physiology.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers identify RBFox1 as a key intrinsic regulator of heart muscle cell maturation, overcoming a major limitation in cardiac regenerative therapy and disease modelling and demonstrating for the first time that RNA splicing control can significantly impact this process. Scientists led by Duke-NUS Medical School in Singapore and the University of California, Los Angeles, (UCLA) [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-179886","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/179886","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=179886"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/179886\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=179886"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=179886"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=179886"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}