{"id":179391,"date":"2023-12-28T14:24:57","date_gmt":"2023-12-28T20:24:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/12\/one-car-t-cell-therapy-for-blood-cancers"},"modified":"2023-12-28T14:24:57","modified_gmt":"2023-12-28T20:24:57","slug":"one-car-t-cell-therapy-for-blood-cancers","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/12\/one-car-t-cell-therapy-for-blood-cancers","title":{"rendered":"One CAR T-Cell Therapy for Blood Cancers?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/one-car-t-cell-therapy-for-blood-cancers.jpg\"><\/a><\/p>\n<p>In the <em>Lord of the Rings<\/em>, there was \u201cone ring to rule them all.\u201d Now, a team of researchers is developing their own single ruler, an approach to <a class=\"\" data-glossary-id=\"CDR0000771302\" href=\"https:\/\/www.cancer.gov\/Common\/PopUps\/popDefinition.aspx?id=CDR0000771302&version=Patient&language=en\">CAR T-cell therapy<\/a> that could treat all forms and types of blood cancer.<\/p>\n<p>In experiments in mouse models of different blood cancers, the treatment <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37651540\/\">rapidly eliminated tumors, including in mice with acute myeloid leukemia (AML)<\/a>, a difficult-to-treat type of blood cancer for which researchers have struggled to develop effective immunotherapies.<\/p>\n<p>There was also no evidence of serious side effects in the animals. And, finally\u2014and distinctly from the standard approach to current CAR T-cell therapies\u2014it provided the mice with a healthy supply of new blood cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the Lord of the Rings, there was \u201cone ring to rule them all.\u201d Now, a team of researchers is developing their own single ruler, an approach to CAR T-cell therapy that could treat all forms and types of blood cancer. In experiments in mouse models of different blood cancers, the treatment rapidly eliminated tumors, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-179391","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/179391","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=179391"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/179391\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=179391"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=179391"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=179391"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}