{"id":178571,"date":"2023-12-18T10:23:40","date_gmt":"2023-12-18T16:23:40","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/12\/a-crispr-pioneer-looks-back-as-the-first-gene-editing-therapy-is-approved"},"modified":"2023-12-18T10:23:40","modified_gmt":"2023-12-18T16:23:40","slug":"a-crispr-pioneer-looks-back-as-the-first-gene-editing-therapy-is-approved","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/12\/a-crispr-pioneer-looks-back-as-the-first-gene-editing-therapy-is-approved","title":{"rendered":"A CRISPR pioneer looks back as the first gene-editing therapy is approved"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-crispr-pioneer-looks-back-as-the-first-gene-editing-therapy-is-approved.jpg\"><\/a><\/p>\n<p>In 2007, <a href=\"https:\/\/www.rockefeller.edu\/our-scientists\/heads-of-laboratories\/982-luciano-marraffini\/\">Luciano Marraffini<\/a> struck out on what was then a scientifically lonely path: to understand CRISPR, which had been discovered in bacteria only about a decade before.<\/p>\n<p>Seventeen years later, we all know what CRISPR is: a revolution in medicine. A once-in-a-lifetime scientific breakthrough. The most promising tool for gene therapy ever discovered. But back then, \u201cclustered regularly interspaced short palindromic repeats\u201d were merely curious genetic fragments with no known purpose.<\/p>\n<p>\u201cWhen I started, there was nothing that indicated that it was going to one day help people to cure genetic diseases,\u201d Marraffini recalls.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In 2007, Luciano Marraffini struck out on what was then a scientifically lonely path: to understand CRISPR, which had been discovered in bacteria only about a decade before. Seventeen years later, we all know what CRISPR is: a revolution in medicine. A once-in-a-lifetime scientific breakthrough. The most promising tool for gene therapy ever discovered. But [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-178571","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/178571","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=178571"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/178571\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=178571"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=178571"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=178571"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}