{"id":177873,"date":"2023-12-08T22:22:27","date_gmt":"2023-12-09T04:22:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/12\/researchers-crack-the-cellular-code-on-protein-folding-offering-hope-for-many-new-therapeutic-avenues"},"modified":"2023-12-08T22:22:27","modified_gmt":"2023-12-09T04:22:27","slug":"researchers-crack-the-cellular-code-on-protein-folding-offering-hope-for-many-new-therapeutic-avenues","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/12\/researchers-crack-the-cellular-code-on-protein-folding-offering-hope-for-many-new-therapeutic-avenues","title":{"rendered":"Researchers crack the cellular code on protein folding, offering hope for many new therapeutic avenues"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researchers-crack-the-cellular-code-on-protein-folding-offering-hope-for-many-new-therapeutic-avenues2.jpg\"><\/a><\/p>\n<p>While we often think of diseases as caused by foreign bodies\u2014bacteria or viruses\u2014there are hundreds of diseases affecting humans that result from errors in cellular production of proteins.<\/p>\n<p>A team of researchers led by the University of Massachusetts Amherst leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy.<\/p>\n<p>The research, <a href=\"https:\/\/www.cell.com\/molecular-cell\/fulltext\/S1097-2765(23)00922-X\">published<\/a> in the journal <i>Molecular Cell<\/i>, explores members of a family of proteins called serpins, which are implicated in a number of diseases. The research is the first to investigate how the location and composition of carbohydrates attached to the serpins ensure that they fold correctly.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>While we often think of diseases as caused by foreign bodies\u2014bacteria or viruses\u2014there are hundreds of diseases affecting humans that result from errors in cellular production of proteins. A team of researchers led by the University of Massachusetts Amherst leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1522],"tags":[],"class_list":["post-177873","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-innovation"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/177873","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=177873"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/177873\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=177873"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=177873"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=177873"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}