{"id":177252,"date":"2023-12-02T07:25:40","date_gmt":"2023-12-02T13:25:40","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/12\/spatiotemporal-control-of-rna-metabolism-and-crispr-cas-functions-using-engineered-photoswitchable-rna-binding-proteins"},"modified":"2023-12-02T07:25:40","modified_gmt":"2023-12-02T13:25:40","slug":"spatiotemporal-control-of-rna-metabolism-and-crispr-cas-functions-using-engineered-photoswitchable-rna-binding-proteins","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/12\/spatiotemporal-control-of-rna-metabolism-and-crispr-cas-functions-using-engineered-photoswitchable-rna-binding-proteins","title":{"rendered":"Spatiotemporal control of RNA metabolism and CRISPR\u2013Cas functions using engineered photoswitchable RNA-binding proteins"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/spatiotemporal-control-of-rna-metabolism-and-crispr-cas-functions-using-engineered-photoswitchable-rna-binding-proteins2.jpg\"><\/a><\/p>\n<p>This protocol for the spatiotemporal control of RNA activity uses LicV, a synthetic, photoswitchable RNA-binding protein (RBP) that can bind to a specific RNA sequence in response to blue light irradiation, and provides an efficient and generalizable strategy for engineering photoswitchable RBPs.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This protocol for the spatiotemporal control of RNA activity uses LicV, a synthetic, photoswitchable RNA-binding protein (RBP) that can bind to a specific RNA sequence in response to blue light irradiation, and provides an efficient and generalizable strategy for engineering photoswitchable RBPs.<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38],"tags":[],"class_list":["post-177252","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/177252","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=177252"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/177252\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=177252"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=177252"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=177252"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}