{"id":17631,"date":"2015-09-21T05:48:35","date_gmt":"2015-09-21T12:48:35","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2015\/09\/chemists-create-assembly-line-for-organic-molecules"},"modified":"2017-06-04T11:37:59","modified_gmt":"2017-06-04T18:37:59","slug":"chemists-create-assembly-line-for-organic-molecules","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2015\/09\/chemists-create-assembly-line-for-organic-molecules","title":{"rendered":"Chemists create \u2018assembly-line\u2019 for organic molecules"},"content":{"rendered":"<p><\/p>\n<p><iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/103825916?title=0&amp;byline=0&amp;portrait=0\" width=\"500\" height=\"281\" frameborder=\"0\" webkitallowfullscreen=\"\" mozallowfullscreen=\"\" allowfullscreen=\"\"><\/iframe><\/p>\n<p>(Phys.org) \u2014Scientists at the University of Bristol have developed a process where reagents are added to a growing carbon chain with extraordinary high fidelity and precise orientation, thereby controlling the conformation of the molecule so that it adopts a helical or linear shape. The process can be likened to a molecular assembly line.<\/p>\n<p>Nature has evolved highly sophisticated machinery for <a href=\"http:\/\/m.phys.org\/tags\/organic+synthesis\/\" rel=\"tag\" class=\"textTag\">organic synthesis<\/a>. One of the most beautiful examples is its machinery for the synthesis of polyketides, a very important class of molecules due to their broad spectrum of biological activities (for example antibiotic, antitumor, antifungal, antiparasitic).<\/p>\n<p>In this process, a simple thioester (small building block) is passed from one enzyme domain to another, growing as it does so until the <a href=\"http:\/\/m.phys.org\/tags\/target+molecule\/\" rel=\"tag\" class=\"textTag\">target molecule<\/a> is formed. The process resembles a molecular assembly line.<\/p>\n<p><a href=\"http:\/\/phys.org\/news\/2014-09-chemists-assembly-line-molecules.html\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Phys.org) \u2014Scientists at the University of Bristol have developed a process where reagents are added to a growing carbon chain with extraordinary high fidelity and precise orientation, thereby controlling the conformation of the molecule so that it adopts a helical or linear shape. The process can be likened to a molecular assembly line. Nature has [\u2026]<\/p>\n","protected":false},"author":367,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-17631","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/17631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/367"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=17631"}],"version-history":[{"count":3,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/17631\/revisions"}],"predecessor-version":[{"id":64126,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/17631\/revisions\/64126"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=17631"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=17631"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=17631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}