{"id":175606,"date":"2023-11-08T01:23:00","date_gmt":"2023-11-08T07:23:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/11\/lung-cancer-researchers-identify-specific-genetic-change-that-predicts-whether-patients-can-respond-to-targeted-therapy"},"modified":"2023-11-08T01:23:00","modified_gmt":"2023-11-08T07:23:00","slug":"lung-cancer-researchers-identify-specific-genetic-change-that-predicts-whether-patients-can-respond-to-targeted-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/11\/lung-cancer-researchers-identify-specific-genetic-change-that-predicts-whether-patients-can-respond-to-targeted-therapy","title":{"rendered":"Lung cancer researchers identify specific genetic change that predicts whether patients can respond to targeted therapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/lung-cancer-researchers-identify-specific-genetic-change-that-predicts-whether-patients-can-respond-to-targeted-therapy2.jpg\"><\/a><\/p>\n<p>Squamous cell lung cancer is a lung cancer subtype that is particularly difficult to treat. A new study now has revealed a novel genetic alteration that occurs in some cases in this type of tumor and that may expose a weakness of the tumor for therapeutic intervention.<\/p>\n<p>The University of Cologne researchers led by Professor Roman Thomas, director of the Department of Translational Genomics, was able to show that a certain genetic change occurs during tumor formation and that a previously unknown oncogene is produced. Oncogenes are genes that promote the growth of tumors. In some cases, they can be inhibited by targeted drug treatments.<\/p>\n<p>This approach is often accompanied by a higher success rate and lower side effects compared to conventional chemotherapy. The scientists\u2019 discovery could therefore be a first step toward a more successful therapy of this particular type of cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Squamous cell lung cancer is a lung cancer subtype that is particularly difficult to treat. A new study now has revealed a novel genetic alteration that occurs in some cases in this type of tumor and that may expose a weakness of the tumor for therapeutic intervention. The University of Cologne researchers led by Professor [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-175606","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/175606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=175606"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/175606\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=175606"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=175606"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=175606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}