{"id":175574,"date":"2023-11-07T16:22:54","date_gmt":"2023-11-07T22:22:54","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/11\/obesity-linked-to-neurodegeneration-through-insulin-resistance"},"modified":"2023-11-07T16:22:54","modified_gmt":"2023-11-07T22:22:54","slug":"obesity-linked-to-neurodegeneration-through-insulin-resistance","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/11\/obesity-linked-to-neurodegeneration-through-insulin-resistance","title":{"rendered":"Obesity linked to neurodegeneration through insulin resistance"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/obesity-linked-to-neurodegeneration-through-insulin-resistance.jpg\"><\/a><\/p>\n<p>Researchers led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center in the United States have discovered a link between obesity and neurodegenerative disorders like Alzheimer\u2019s disease.<\/p>\n<p>Using the common fruit fly, the research shows that a high-sugar diet\u2014a hallmark of obesity\u2014causes <a href=\"https:\/\/medicalxpress.com\/tags\/insulin+resistance\/\" rel=\"tag\" class=\"\">insulin resistance<\/a> in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.<\/p>\n<p>Publishing November 7 in the open access journal <a href=\"http:\/\/journals.plos.org\/plosbiology\/article?id=10.1371\/journal.pbio.3002359\">PLOS Biology<\/a>, the research will impact therapies designed to reduce the risk of developing <a href=\"https:\/\/medicalxpress.com\/tags\/neurodegenerative+diseases\/\" rel=\"tag\" class=\"\">neurodegenerative diseases<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center in the United States have discovered a link between obesity and neurodegenerative disorders like Alzheimer\u2019s disease. Using the common fruit fly, the research shows that a high-sugar diet\u2014a hallmark of obesity\u2014causes insulin resistance in the brain, which in turn reduces the ability to [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-175574","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/175574","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=175574"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/175574\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=175574"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=175574"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=175574"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}