{"id":173740,"date":"2023-10-08T06:25:55","date_gmt":"2023-10-08T11:25:55","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/10\/rare-mutation-may-counteract-alzheimers-gene"},"modified":"2023-10-08T06:25:55","modified_gmt":"2023-10-08T11:25:55","slug":"rare-mutation-may-counteract-alzheimers-gene","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/10\/rare-mutation-may-counteract-alzheimers-gene","title":{"rendered":"Rare mutation may counteract \u201cAlzheimer\u2019s gene\u201d"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/rare-mutation-may-counteract-alzheimers-gene2.jpg\"><\/a><\/p>\n<p><strong>The challenge:<\/strong> There are very few ways to slow down Alzheimer\u2019s disease or treat its symptoms, and there\u2019s no cure \u2014 in 2021, <a href=\"https:\/\/www.cdc.gov\/nchs\/fastats\/leading-causes-of-death.htm\">nearly 120,000<\/a> Americans died from Alzheimer\u2019s complications, making it one of the top 10 leading causes of death.<\/p>\n<p>One genetic variant in particular \u2014 called <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/alzheimers-disease\/in-depth\/alzheimers-genes\/art-20046552\">APOE-e4<\/a> \u2014 is strongly tied to the brain disease. Having one copy makes a person 2\u20133 times more likely to develop Alzheimer\u2019s, while having two copies (one from each parent) increases the risk by 8\u201312 times.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The challenge: There are very few ways to slow down Alzheimer\u2019s disease or treat its symptoms, and there\u2019s no cure \u2014 in 2021, nearly 120,000 Americans died from Alzheimer\u2019s complications, making it one of the top 10 leading causes of death. One genetic variant in particular \u2014 called APOE-e4 \u2014 is strongly tied to the [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-173740","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/173740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=173740"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/173740\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=173740"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=173740"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=173740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}