{"id":173150,"date":"2023-09-29T21:31:29","date_gmt":"2023-09-30T02:31:29","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/optimizing-car-t-cell-therapy-with-bridging-radiation-therapy"},"modified":"2023-09-29T21:31:29","modified_gmt":"2023-09-30T02:31:29","slug":"optimizing-car-t-cell-therapy-with-bridging-radiation-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/optimizing-car-t-cell-therapy-with-bridging-radiation-therapy","title":{"rendered":"Optimizing CAR T cell therapy with bridging radiation therapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/optimizing-car-t-cell-therapy-with-bridging-radiation-therapy.jpg\"><\/a><\/p>\n<p>For many patients diagnosed with certain types of <a href=\"https:\/\/www.mdanderson.org\/cancer-types\/non-hodgkin-lymphoma.html\">B-cell lymphoma<\/a>, <a href=\"https:\/\/www.mdanderson.org\/cancer-types\/leukemia.html\">leukemia<\/a> and <a href=\"https:\/\/www.mdanderson.org\/cancer-types\/multiple-myeloma.html\">multiple myeloma<\/a>, <a href=\"https:\/\/www.mdanderson.org\/treatment-options\/car-t-cell-therapy.html\">chimeric antigen receptor (CAR) T cell therapy<\/a> offers an effective treatment option. This cellular therapy is created by extracting a patient\u2019s T cells, modifying them in a lab to identify and attack cancer cells, and returning them to the patient.<\/p>\n<p>The process of creating the CAR T cells can take three to four weeks. <a href=\"https:\/\/www.mdanderson.org\/treatment-options\/radiation-therapy.html\">Radiation therapy<\/a> can be a tool to help get a patient through this manufacturing period. This is called bridging therapy.<\/p>\n<p>\u201cBridging therapy can help control the disease so that a patient can get to the CAR T cell infusion,\u201d says radiation oncologist <a href=\"http:\/\/faculty.mdanderson.org\/profiles\/penny_fang.html\">Penny Fang, M.D.<\/a> Research from Fang and her colleagues examines the role of bridging therapy for B-cell lymphoma patients receiving CAR T cell therapy. Their latest findings will be presented at the <a href=\"https:\/\/www.mdanderson.org\/research\/research-resources\/conferences-seminars\/md-anderson-at-astro.html\">2023 American Society for Radiation Oncology Annual Meeting<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>For many patients diagnosed with certain types of B-cell lymphoma, leukemia and multiple myeloma, chimeric antigen receptor (CAR) T cell therapy offers an effective treatment option. This cellular therapy is created by extracting a patient\u2019s T cells, modifying them in a lab to identify and attack cancer cells, and returning them to the patient. The [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-173150","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/173150","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=173150"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/173150\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=173150"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=173150"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=173150"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}