{"id":172926,"date":"2023-09-27T20:26:24","date_gmt":"2023-09-28T01:26:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/ucla-led-advancement-redefines-nobel-prize-winning-technology"},"modified":"2023-09-27T20:26:24","modified_gmt":"2023-09-28T01:26:24","slug":"ucla-led-advancement-redefines-nobel-prize-winning-technology","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/ucla-led-advancement-redefines-nobel-prize-winning-technology","title":{"rendered":"UCLA-led advancement redefines Nobel Prize-winning technology"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/ucla-led-advancement-redefines-nobel-prize-winning-technology2.jpg\"><\/a><\/p>\n<p>Using their new scaffold with cryo-EM, the UCLA-led team saw the atomic structure of KRAS when it was connected to a drug being studied for lung cancer treatment. This showed that their method can help understand how drugs interact with proteins like KRAS, potentially leading to better medicines.<\/p>\n<p>Castells-Graells <a href=\"https:\/\/newsroom.ucla.edu\/releases\/tripod-tethers-advance-in-cryo-electron-microscopy\">said<\/a>,<em> \u201cThe potential applications for the new advance don\u2019t stop with <a href=\"https:\/\/www.techexplorist.com\/new-method-for-controlled-release-makes-cancer-drugs-less-toxic-to-healthy-tissues\/22551\/\">cancer drugs<\/a>. \u201d Our modular scaffold can be assembled in any configuration to capture and hold all small protein molecules.\u201d<\/em><\/p>\n<p>The UCLA-led team\u2019s essential improvement to cryo-EM <a href=\"https:\/\/www.techexplorist.com\/tag\/technology\/\">technology<\/a> represents a significant milestone in structural biology and scientific imaging. Their achievement in visualizing small therapeutic protein targets at 3 \u00c5 resolution is a testament to the power of innovation and collaboration in pushing the boundaries of scientific discovery. This breakthrough promises to revolutionize <a href=\"https:\/\/www.techexplorist.com\/tag\/drug\/\">drug<\/a> development and our understanding of complex biological systems, further solidifying Cryo-EM\u2019s place as an invaluable tool in modern research.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using their new scaffold with cryo-EM, the UCLA-led team saw the atomic structure of KRAS when it was connected to a drug being studied for lung cancer treatment. This showed that their method can help understand how drugs interact with proteins like KRAS, potentially leading to better medicines. Castells-Graells said, \u201cThe potential applications for the [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1522],"tags":[],"class_list":["post-172926","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-innovation"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=172926"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172926\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=172926"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=172926"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=172926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}