{"id":172799,"date":"2023-09-26T00:22:24","date_gmt":"2023-09-26T05:22:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/regeneration-across-complete-spinal-cord-injuries-reverses-paralysis"},"modified":"2023-09-26T00:22:24","modified_gmt":"2023-09-26T05:22:24","slug":"regeneration-across-complete-spinal-cord-injuries-reverses-paralysis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/regeneration-across-complete-spinal-cord-injuries-reverses-paralysis","title":{"rendered":"Regeneration across complete spinal cord injuries reverses paralysis"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/2RxBbqYmTqA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>When the spinal cords of mice and humans are partially damaged, the initial paralysis is followed by the extensive, spontaneous recovery of motor function. However, after a complete spinal cord injury, this natural repair of the spinal cord doesn\u2019t occur and there is no recovery. Meaningful recovery after severe injuries requires strategies that promote the regeneration of nerve fibers, but the requisite conditions for these strategies to successfully restore motor function have remained elusive.<\/p>\n<p>\u201cFive years ago, we demonstrated that <a href=\"https:\/\/medicalxpress.com\/tags\/nerve+fibers\/\" rel=\"tag\" class=\"\">nerve fibers<\/a> can be regenerated across anatomically complete spinal cord injuries,\u201d says Mark Anderson, a senior author of the study. \u201cBut we also realized this wasn\u2019t enough to restore motor function, as the new fibers failed to connect to the right places on the other side of the lesion.\u201d Anderson is the director of Central Nervous System Regeneration at. NeuroRestore and a scientist at the Wyss Center for Bio and Neuroengineering.<\/p>\n<p>Working in tandem with peers at UCLA and Harvard Medical School, the scientists used state-of-the-art equipment at EPFL\u2019s Campus Biotech facilities in Geneva to run in-depth analyses and identity which type of neuron is involved in natural spinal-cord repair after partial spinal cord injury.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When the spinal cords of mice and humans are partially damaged, the initial paralysis is followed by the extensive, spontaneous recovery of motor function. However, after a complete spinal cord injury, this natural repair of the spinal cord doesn\u2019t occur and there is no recovery. Meaningful recovery after severe injuries requires strategies that promote the [\u2026]<\/p>\n","protected":false},"author":359,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38,47],"tags":[],"class_list":["post-172799","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172799","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/359"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=172799"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172799\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=172799"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=172799"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=172799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}