{"id":172645,"date":"2023-09-23T16:22:26","date_gmt":"2023-09-23T21:22:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/step-forward-for-massive-dna-computer-systems"},"modified":"2023-09-23T16:22:26","modified_gmt":"2023-09-23T21:22:26","slug":"step-forward-for-massive-dna-computer-systems","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/step-forward-for-massive-dna-computer-systems","title":{"rendered":"Step forward for massive DNA computer systems"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/step-forward-for-massive-dna-computer-systems2.jpg\"><\/a><\/p>\n<p>The group at Shanghai Jiao Tong University has demonstrated a DNA computer system using DNA integrated circuits (DICs) that can solve quadratic equations with 30 logic gates.<\/p>\n<p>Published in Nature, the system integrates multiple layers of DNA-based programmable gate arrays (DPGAs). This uses generic single-stranded oligonucleotides as a uniform transmission signal can reliably integrate large-scale DICs with minimal leakage and high fidelity for general-purpose computing.<\/p>\n<p>To control the intrinsically random collision of molecules, the team designed DNA origami registers to provide the directionality for asynchronous execution of cascaded DPGAs. This was used to assemble a DIC that can solve quadratic equations with three layers of cascade DPGAs comprising 30 logic gates with around 500 DNA strands.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The group at Shanghai Jiao Tong University has demonstrated a DNA computer system using DNA integrated circuits (DICs) that can solve quadratic equations with 30 logic gates. Published in Nature, the system integrates multiple layers of DNA-based programmable gate arrays (DPGAs). This uses generic single-stranded oligonucleotides as a uniform transmission signal can reliably integrate large-scale [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523,41],"tags":[],"class_list":["post-172645","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing","category-information-science"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172645","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=172645"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172645\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=172645"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=172645"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=172645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}