{"id":172544,"date":"2023-09-22T04:22:56","date_gmt":"2023-09-22T09:22:56","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/rewiring-tumor-mitochondria-enhances-the-immune-systems-ability-to-recognize-and-fight-cancer"},"modified":"2023-09-22T04:22:56","modified_gmt":"2023-09-22T09:22:56","slug":"rewiring-tumor-mitochondria-enhances-the-immune-systems-ability-to-recognize-and-fight-cancer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/rewiring-tumor-mitochondria-enhances-the-immune-systems-ability-to-recognize-and-fight-cancer","title":{"rendered":"Rewiring tumor mitochondria enhances the immune system\u2019s ability to recognize and fight cancer"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/rewiring-tumor-mitochondria-enhances-the-immune-systems-ability-to-recognize-and-fight-cancer2.jpg\"><\/a><\/p>\n<p>Immunotherapy, which uses the body\u2019s own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it. Thus, cancer researchers are seeking new ways to optimize immunotherapy so that it is more effective for more people.<\/p>\n<p>Now, Salk Institute scientists have found that manipulating an early step in <a href=\"https:\/\/medicalxpress.com\/tags\/energy+production\/\" rel=\"tag\" class=\"\">energy production<\/a> in mitochondria\u2014the cell\u2019s powerhouses\u2014reduces melanoma <a href=\"https:\/\/medicalxpress.com\/tags\/tumor\/\" rel=\"tag\" class=\"\">tumor<\/a> growth and enhances the <a href=\"https:\/\/medicalxpress.com\/tags\/immune+response\/\" rel=\"tag\" class=\"\">immune response<\/a> in mice.<\/p>\n<p>The study, published in <a href=\"http:\/\/www.science.org\/doi\/10.1126\/science.abq1053\">Science<\/a> on September 21, 2023, revealed that when electrons take one of two initial routes through mitochondria, genes and proteins become activated that are needed for <a href=\"https:\/\/medicalxpress.com\/tags\/immune+cells\/\" rel=\"tag\" class=\"\">immune cells<\/a> to recognize and kill <a href=\"https:\/\/medicalxpress.com\/tags\/tumor+cells\/\" rel=\"tag\" class=\"\">tumor cells<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Immunotherapy, which uses the body\u2019s own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it. Thus, cancer researchers are seeking new ways to optimize immunotherapy so that it is more effective for more people. Now, Salk Institute scientists have found that manipulating an early step in [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-172544","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=172544"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172544\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=172544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=172544"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=172544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}