{"id":172470,"date":"2023-09-20T23:25:01","date_gmt":"2023-09-21T04:25:01","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/study-reveals-structure-of-crucial-receptor-in-brain-development-and-its-function"},"modified":"2023-09-20T23:25:01","modified_gmt":"2023-09-21T04:25:01","slug":"study-reveals-structure-of-crucial-receptor-in-brain-development-and-its-function","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/study-reveals-structure-of-crucial-receptor-in-brain-development-and-its-function","title":{"rendered":"Study reveals structure of crucial receptor in brain development and its function"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/study-reveals-structure-of-crucial-receptor-in-brain-development-and-its-function2.jpg\"><\/a><\/p>\n<p>Scientists have revealed the molecular structure of a type of receptor that\u2019s crucial to brain development and function.<\/p>\n<p>Known as Type A GABA receptors, these receptors are already targeted by pharmaceutical anesthetics, sedatives and antidepressants because of their important role in <a href=\"https:\/\/medicalxpress.com\/tags\/brain+function\/\" rel=\"tag\" class=\"\">brain function<\/a>. The discovery, <a href=\"https:\/\/www.nature.com\/articles\/s41586-023-06556-w\">published today in the journal <i>Nature<\/i><\/a>, reveals the dominant assemblies and states of the GABA receptor, a finding that could enable the development of new compounds that more specifically target a range of medical disorders.<\/p>\n<p>\u201cIt is the main player that balances excitation and inhibition in the brain,\u201d said lead author Chang Sun, Ph.D., a postdoctoral researcher in the Vollum Institute at Oregon Health &amp; Science University. \u201cIt affects all aspects of brain function, from motor function, to memory and learning, and also emotion and anxiety.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists have revealed the molecular structure of a type of receptor that\u2019s crucial to brain development and function. Known as Type A GABA receptors, these receptors are already targeted by pharmaceutical anesthetics, sedatives and antidepressants because of their important role in brain function. The discovery, published today in the journal Nature, reveals the dominant assemblies [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-172470","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172470","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=172470"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172470\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=172470"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=172470"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=172470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}