{"id":17222,"date":"2015-09-14T03:47:02","date_gmt":"2015-09-14T10:47:02","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2015\/09\/aging-causes-muscle-weakness-and-atrophy-but-can-we-treat-it"},"modified":"2017-06-04T11:41:11","modified_gmt":"2017-06-04T18:41:11","slug":"aging-causes-muscle-weakness-and-atrophy-but-can-we-treat-it","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2015\/09\/aging-causes-muscle-weakness-and-atrophy-but-can-we-treat-it","title":{"rendered":"Aging Causes Muscle Weakness And Atrophy, But Can We Treat It?"},"content":{"rendered":"<p><a class=\\'blog-photo\\' href=\"https:\/\/lifeboat.com\/blog.images\/aging-causes-muscle-weakness-and-atrophy-but-can-we-treat-it.jpg\"><\/a><\/p>\n<p>Everything starts to go downhill as we get older and muscle is no exception; even simple tasks become challenging as we lose bone and muscle. Now research has identified a protein behind this age-related decline and therapeutic molecules that can fight it, helping individuals stay healthy and strong for longer.<\/p>\n<p>A team at the Univesity of Iowa has discovered that a protein called ATF4 might be behind muscular decline. ATF 4 is a transcription factor, which means it tells the body to activate or regulate certain genes. ATF4 seems to change skeletal muscle with age, reducing protein synthesis and overall mass.<\/p>\n<p><em><strong>\u201dMany of us know from our own experiences that muscle weakness and atrophy are big problems as we become older\u201d<\/strong><\/em><\/p>\n<p><em><strong>What can we do about it?<\/strong><\/em><\/p>\n<p>Researchers also identified two molecules that dramatically reduce this age-related decline in mice: <strong>ursolic acid <\/strong>from apple peels, and <strong>tomatidine<\/strong>, present in green tomatoes. When elderly mice were fed either of these compounds, muscle mass was increased by 10% and muscle strength by 30% \u2014 essentially restoring their muscles to a youthful state.<\/p>\n<p><a href=\"http:\/\/www.longevityreporter.org\/blog\/2015\/9\/9\/age-brings-muscle-weakness-and-atrophy-but-can-we-treat-it\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Everything starts to go downhill as we get older and muscle is no exception; even simple tasks become challenging as we lose bone and muscle. Now research has identified a protein behind this age-related decline and therapeutic molecules that can fight it, helping individuals stay healthy and strong for longer. A team at the Univesity [\u2026]<\/p>\n","protected":false},"author":259,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1495,269],"tags":[],"class_list":["post-17222","post","type-post","status-publish","format-standard","hentry","category-health","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/17222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/259"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=17222"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/17222\/revisions"}],"predecessor-version":[{"id":64229,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/17222\/revisions\/64229"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=17222"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=17222"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=17222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}