{"id":172136,"date":"2023-09-16T07:22:49","date_gmt":"2023-09-16T12:22:49","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/antibody-prevents-graft-versus-host-disease-in-preclinical-tests"},"modified":"2023-09-16T07:22:49","modified_gmt":"2023-09-16T12:22:49","slug":"antibody-prevents-graft-versus-host-disease-in-preclinical-tests","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/antibody-prevents-graft-versus-host-disease-in-preclinical-tests","title":{"rendered":"Antibody Prevents Graft Versus Host Disease in Preclinical Tests"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/antibody-prevents-graft-versus-host-disease-in-preclinical-tests.jpg\"><\/a><\/p>\n<p>Even when a bone marrow transplant cures leukemia or lymphoma, GVHD\u2014in which T cells in the donor graft attack the recipient\u2019s own tissues\u2014can still be fatal. The condition is among the leading causes of death and long-term adverse health consequences associated with bone marrow transplants.<\/p>\n<p>Senior co-corresponding authors Ivan Maillard, MD, PhD, a professor of Medicine and vice chief for research in Hematology-Oncology at the Perelman School of Medicine at the University of Pennsylvania, and Leslie S. Kean, MD, PhD, a professor of Pediatrics at Harvard Medical School and director of Pediatric Stem Cell Transplant at Dana-Farber\/Boston Children\u2019s Cancer and Blood Disorders Center, along with\u2026 More.<\/p>\n<hr>\n<p>In new preclinical research, an experimental antibody treatment largely prevented a bone marrow transplant complication called graft versus host disease in the intestines, without causing broad immune suppression, paving the way for clinical trials.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Even when a bone marrow transplant cures leukemia or lymphoma, GVHD\u2014in which T cells in the donor graft attack the recipient\u2019s own tissues\u2014can still be fatal. The condition is among the leading causes of death and long-term adverse health consequences associated with bone marrow transplants. Senior co-corresponding authors Ivan Maillard, MD, PhD, a professor of [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-172136","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172136","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=172136"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/172136\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=172136"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=172136"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=172136"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}