{"id":171146,"date":"2023-09-02T22:22:56","date_gmt":"2023-09-03T03:22:56","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/holy-grail-molecule-kills-all-types-of-solid-cancer-tumors"},"modified":"2023-09-02T22:22:56","modified_gmt":"2023-09-03T03:22:56","slug":"holy-grail-molecule-kills-all-types-of-solid-cancer-tumors","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/holy-grail-molecule-kills-all-types-of-solid-cancer-tumors","title":{"rendered":"\u201cHoly grail\u201d molecule kills all types of solid cancer tumors"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/holy-grail-molecule-kills-all-types-of-solid-cancer-tumors2.jpg\"><\/a><\/p>\n<p>A team of scientists at the <a href=\"https:\/\/www.cityofhope.org\/\">City of Hope Hospital<\/a> \u2013 one of the largest <a href=\"https:\/\/www.earth.com\/news\/cannabis-may-be-a-highly-effective-treatment-for-cancer-patients\/\">cancer<\/a> research and treatment organizations in the United States \u2013 has recently developed what could potentially be a \u201choly grail\u201d molecule that can effectively eradicate all solid cancer tumors while leaving healthy cells unaffected.<\/p>\n<p>In preclinical trials, this molecule \u2013 called AOH1996 \u2013 was found to target and eradicate the proliferating cell nuclear antigen (PCNA) protein, which usually contributes to the growth and repair of a variety of cancer tumors.<\/p>\n<p>Most of the previous targeted anti-cancer therapies focus on a single pathway, enabling cancers to mutate and eventually become resistant. By contrast, since AOH1996 targets a cancerous variant of PCNA, a protein that in its mutated form is crucial in DNA replication and repair of all types of tumors, its effectiveness is higher and its range of action significantly broader.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of scientists at the City of Hope Hospital \u2013 one of the largest cancer research and treatment organizations in the United States \u2013 has recently developed what could potentially be a \u201choly grail\u201d molecule that can effectively eradicate all solid cancer tumors while leaving healthy cells unaffected. In preclinical trials, this molecule \u2013 [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-171146","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/171146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=171146"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/171146\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=171146"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=171146"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=171146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}