{"id":171111,"date":"2023-09-02T01:34:09","date_gmt":"2023-09-02T06:34:09","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/09\/innovative-insights-into-effects-of-hematopoietic-changes-on-colon-cancer-unveiling-therapeutic-avenues"},"modified":"2023-09-02T01:34:09","modified_gmt":"2023-09-02T06:34:09","slug":"innovative-insights-into-effects-of-hematopoietic-changes-on-colon-cancer-unveiling-therapeutic-avenues","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/09\/innovative-insights-into-effects-of-hematopoietic-changes-on-colon-cancer-unveiling-therapeutic-avenues","title":{"rendered":"Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/innovative-insights-into-effects-of-hematopoietic-changes-on-colon-cancer-unveiling-therapeutic-avenues2.jpg\"><\/a><\/p>\n<p>In a recent study published in the <a href=\"https:\/\/rupress.org\/jem\/article\/220\/11\/e20230011\/276202\/\" target=\"_blank\" rel=\"noopener\">Journal of Experimental Medicine<\/a>, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a<sup>+\/\u0394<\/sup>), the most common genetic alteration in clonal hematopoiesis (CH), contribute to colitis-associated colon cancer (CAC) pathogenesis.<\/p>\n<p>Study: Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer. Image Credit: <a href=\"http:\/\/vetpathologist\/Shutterstock.com\">vetpathologist\/Shutterstock.com<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a recent study published in the Journal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+\/\u0394), the most common genetic alteration in clonal hematopoiesis (CH), contribute to colitis-associated colon cancer (CAC) pathogenesis. Study: Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer. Image Credit: vetpathologist\/Shutterstock.com.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-171111","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/171111","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=171111"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/171111\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=171111"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=171111"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=171111"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}