{"id":171022,"date":"2023-08-31T17:33:00","date_gmt":"2023-08-31T22:33:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/08\/a-new-biological-mechanism-to-regenerate-and-repair-myelin"},"modified":"2023-08-31T17:33:00","modified_gmt":"2023-08-31T22:33:00","slug":"a-new-biological-mechanism-to-regenerate-and-repair-myelin","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/08\/a-new-biological-mechanism-to-regenerate-and-repair-myelin","title":{"rendered":"A new biological mechanism to regenerate and repair myelin"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-new-biological-mechanism-to-regenerate-and-repair-myelin.jpg\"><\/a><\/p>\n<p>A neonatal hypoxic-injury animal model revealed that CK2\u03b1 mediated Daam2 phosphorylation, which plays a protective role in developmental and behavioral recovery after neonatal hypoxia, a form of brain injury seen in cerebral palsy and other conditions. Additionally, it facilitates remyelination after white matter injury in adult animals.<\/p>\n<blockquote><p>Together, these findings have identified a novel regulatory node connecting CK2\u03b1 and Daam2 in the Wnt pathway that regulates stage-specific oligodendrocyte development and offers insights into a new biological mechanism to regenerate myelin.<\/p><\/blockquote>\n<p>\u201cThis study opens exciting therapeutic avenues we could develop in the future to repair and restore myelin, which has the potential to alleviate and treat several neurological issues that are currently untreatable,\u201d Lee said.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A neonatal hypoxic-injury animal model revealed that CK2\u03b1 mediated Daam2 phosphorylation, which plays a protective role in developmental and behavioral recovery after neonatal hypoxia, a form of brain injury seen in cerebral palsy and other conditions. Additionally, it facilitates remyelination after white matter injury in adult animals. Together, these findings have identified a novel regulatory [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,47],"tags":[],"class_list":["post-171022","post","type-post","status-publish","format-standard","hentry","category-biological","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/171022","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=171022"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/171022\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=171022"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=171022"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=171022"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}