{"id":169894,"date":"2023-08-17T21:27:19","date_gmt":"2023-08-18T02:27:19","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/08\/schizophrenia-drugs-may-have-been-off-target-for-decades-study-finds"},"modified":"2023-08-17T21:27:19","modified_gmt":"2023-08-18T02:27:19","slug":"schizophrenia-drugs-may-have-been-off-target-for-decades-study-finds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/08\/schizophrenia-drugs-may-have-been-off-target-for-decades-study-finds","title":{"rendered":"Schizophrenia Drugs May Have Been Off Target For Decades, Study Finds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/schizophrenia-drugs-may-have-been-off-target-for-decades-study-finds2.jpg\"><\/a><\/p>\n<p>A study that peered into live mouse brains suggests for nearly 70 years we\u2019ve been targeting the wrong neurons in our design of antipsychotic drugs.<\/p>\n<p>Untangling the vast web of brain cells and determining how drugs work upon them is a tough task. Using a miniature microscope and fluorescent tags, a team of researchers led by Northwestern University neuroscientist Seongsik Yun discovered that effective antipsychotic drugs cling to a different type of brain cell than scientists originally thought.<\/p>\n<p>Just like research suggesting <a href=\"https:\/\/www.sciencealert.com\/depression\" class=\"\" rel=\"nofollow\" target=\"_self\">depression<\/a> <a href=\"https:\/\/www.sciencealert.com\/huge-new-study-says-your-depression-isn-t-a-chemical-imbalance-after-all\">might not be a chemical imbalance<\/a> in serotonin levels, our understanding of <a href=\"https:\/\/www.sciencealert.com\/schizophrenia\" class=\"\" rel=\"nofollow\" target=\"_self\">schizophrenia<\/a> treatments may need a rethink if widely-used antipsychotics are targeting different neurons than expected.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study that peered into live mouse brains suggests for nearly 70 years we\u2019ve been targeting the wrong neurons in our design of antipsychotic drugs. Untangling the vast web of brain cells and determining how drugs work upon them is a tough task. Using a miniature microscope and fluorescent tags, a team of researchers led [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,47],"tags":[],"class_list":["post-169894","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169894","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=169894"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169894\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=169894"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=169894"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=169894"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}