{"id":169846,"date":"2023-08-17T05:28:47","date_gmt":"2023-08-17T10:28:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/08\/genetically-modified-neural-stem-cells-show-promising-therapeutic-potential-for-spinal-cord-injury"},"modified":"2023-08-17T05:28:47","modified_gmt":"2023-08-17T10:28:47","slug":"genetically-modified-neural-stem-cells-show-promising-therapeutic-potential-for-spinal-cord-injury","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/08\/genetically-modified-neural-stem-cells-show-promising-therapeutic-potential-for-spinal-cord-injury","title":{"rendered":"Genetically-modified neural stem cells show promising therapeutic potential for spinal cord injury"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/genetically-modified-neural-stem-cells-show-promising-therapeutic-potential-for-spinal-cord-injury3.jpg\"><\/a><\/p>\n<p>A research team co-led by City University of Hong Kong (CityU) and The University of Hong Kong (HKU) has recently made a significant advancement in spinal cord injury treatment by using genetically-modified human neural stem cells (hNSCs).<\/p>\n<p>They found that specifically modulating a <a href=\"https:\/\/medicalxpress.com\/tags\/gene+expression\/\" rel=\"tag\" class=\"\">gene expression<\/a> to a certain level in hNSCs can effectively promote the reconstruction of damaged neural circuits and restore locomotor functions, offering great potential for new therapeutic opportunities for patients with spinal cord <a href=\"https:\/\/medicalxpress.com\/tags\/injury\/\" rel=\"tag\" class=\"\">injury<\/a>. The findings were published in the journal <i>Advanced Science<\/i> under the title \u201cTransplanting Human Neural Stem Cells with \u224850% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury.\u201d<\/p>\n<p>Traumatic spinal cord injury is a devastating condition that commonly results from accidents such as falls, car crashes or sport-related injuries.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A research team co-led by City University of Hong Kong (CityU) and The University of Hong Kong (HKU) has recently made a significant advancement in spinal cord injury treatment by using genetically-modified human neural stem cells (hNSCs). They found that specifically modulating a gene expression to a certain level in hNSCs can effectively promote the [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-169846","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=169846"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169846\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=169846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=169846"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=169846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}