{"id":169807,"date":"2023-08-16T13:25:02","date_gmt":"2023-08-16T18:25:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/08\/new-pcna-inhibitor-aoh1996-shows-selective-cancer-cell-killings-and-tumor-suppression-potential"},"modified":"2023-08-16T13:25:02","modified_gmt":"2023-08-16T18:25:02","slug":"new-pcna-inhibitor-aoh1996-shows-selective-cancer-cell-killings-and-tumor-suppression-potential","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/08\/new-pcna-inhibitor-aoh1996-shows-selective-cancer-cell-killings-and-tumor-suppression-potential","title":{"rendered":"New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-pcna-inhibitor-aoh1996-shows-selective-cancer-cell-killings-and-tumor-suppression-potential2.jpg\"><\/a><\/p>\n<p>A recent study published in the <a href=\"https:\/\/doi.org\/10.1016\/j.chembiol.2023.07.001\" target=\"_blank\" rel=\"noopener\">Cell Chemical Biology<\/a> Journal described a small molecule inhibitor of proliferating cell nuclear <a href=\"https:\/\/www.news-medical.net\/health\/What-is-an-Antigen.aspx\" class=\"\">antigen<\/a> (PCNA) that selectively kills cancer cells.<\/p>\n<p>Study: Small molecule targeting of transcription-replication conflict for selective chemotherapy. Image Credit: <a href=\"http:\/\/Lightspring\/Shutterstock.com\">Lightspring\/Shutterstock.com<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent study published in the Cell Chemical Biology Journal described a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) that selectively kills cancer cells. Study: Small molecule targeting of transcription-replication conflict for selective chemotherapy. Image Credit: Lightspring\/Shutterstock.com.<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19],"tags":[],"class_list":["post-169807","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169807","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=169807"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169807\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=169807"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=169807"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=169807"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}