{"id":169232,"date":"2023-08-08T00:23:17","date_gmt":"2023-08-08T05:23:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/08\/role-of-m2-macrophage-derived-exosomes-in-controlling-neutrophil-mediated-tissue-injury-in-sepsis"},"modified":"2023-08-08T00:23:17","modified_gmt":"2023-08-08T05:23:17","slug":"role-of-m2-macrophage-derived-exosomes-in-controlling-neutrophil-mediated-tissue-injury-in-sepsis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/08\/role-of-m2-macrophage-derived-exosomes-in-controlling-neutrophil-mediated-tissue-injury-in-sepsis","title":{"rendered":"Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/role-of-m2-macrophage-derived-exosomes-in-controlling-neutrophil-mediated-tissue-injury-in-sepsis.jpg\"><\/a><\/p>\n<p>In a recent study published in the <em><a href=\"https:\/\/jbiomedsci.biomedcentral.com\/articles\/10.1186\/s12929-023-00957-9\" rel=\"noopener\">Journal of Biomedical Science<\/a><\/em>, researchers investigate whether M2 macrophage-derived exosomes (M2-Exos) could prevent inflammation-associated damage during sepsis-associated acute lung injury (ALI) by modulating abnormal polymorphonuclear neutrophil (PMN) behaviors.<\/p>\n<p>Study: Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis. Image Credit: Kateryna Kon \/ <a href=\"http:\/\/Shutterstock.com\">Shutterstock.com<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a recent study published in the Journal of Biomedical Science, researchers investigate whether M2 macrophage-derived exosomes (M2-Exos) could prevent inflammation-associated damage during sepsis-associated acute lung injury (ALI) by modulating abnormal polymorphonuclear neutrophil (PMN) behaviors. Study: Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis. Image [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-169232","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=169232"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169232\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=169232"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=169232"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=169232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}