{"id":169036,"date":"2023-08-04T20:24:30","date_gmt":"2023-08-05T01:24:30","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/08\/common-blood-thinner-may-double-as-cancer-therapy"},"modified":"2023-08-04T20:24:30","modified_gmt":"2023-08-05T01:24:30","slug":"common-blood-thinner-may-double-as-cancer-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/08\/common-blood-thinner-may-double-as-cancer-therapy","title":{"rendered":"Common blood thinner may double as cancer therapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/common-blood-thinner-may-double-as-cancer-therapy2.jpg\"><\/a><\/p>\n<p>Warfarin, a widely used blood thinner, appears to have potent anti-cancer properties, according to a study by Columbia University researchers. The study, conducted in human cells and in mice, found that warfarin stops tumors from interfering with a self-destruct mechanism that cells initiate when they detect mutations or other abnormalities.<\/p>\n<p>\u201cOur findings suggest that <a href=\"https:\/\/medicalxpress.com\/tags\/warfarin\/\" rel=\"tag\" class=\"\">warfarin<\/a>, which is already approved by the FDA, could be repurposed to treat a variety of cancers, including pancreatic cancer,\u201d says study leader Wei Gu, Ph.D., the Abraham and Mildred Goldstein Professor of Pathology &amp; Cell Biology (in the Institute for Cancer Genetics) at Columbia University Vagelos College of Physicians and Surgeons.<\/p>\n<p>The study is titled \u201cRegulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism,\u201d and it was published July 18 in <i>Cell Metabolism<\/i>. Postdoctoral researcher scientists Xin Yang, Ph.D., and Zhe Wang, Ph.D., contributed equally as first authors.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Warfarin, a widely used blood thinner, appears to have potent anti-cancer properties, according to a study by Columbia University researchers. The study, conducted in human cells and in mice, found that warfarin stops tumors from interfering with a self-destruct mechanism that cells initiate when they detect mutations or other abnormalities. \u201cOur findings suggest that warfarin, [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-169036","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=169036"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/169036\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=169036"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=169036"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=169036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}