{"id":168427,"date":"2023-07-27T04:23:20","date_gmt":"2023-07-27T09:23:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/07\/how-the-microbiome-influences-immunity-in-drosophila"},"modified":"2023-07-27T04:23:20","modified_gmt":"2023-07-27T09:23:20","slug":"how-the-microbiome-influences-immunity-in-drosophila","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/07\/how-the-microbiome-influences-immunity-in-drosophila","title":{"rendered":"How the Microbiome Influences Immunity in Drosophila"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/how-the-microbiome-influences-immunity-in-drosophila.jpg\"><\/a><\/p>\n<p>Antimicrobial peptides (AMPs)\u2014small peptides that protect against microbial infection\u2014are crucial immune effectors in both plants and animals. They not only fight against potential infections, they also influence the composition of the host\u2019s microbiome. Little is known about the driving forces behind AMPs\u2019 rapid evolution. Now, a study uncovers the selective pressures driving the evolution of AMPs and how they control bacteria in the host\u2019s microbiome.<\/p>\n<p>The work is published in <em>Science<\/em> in the paper, \u201c<a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adg5725\" target=\"_blank\" rel=\"noopener\">Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in <em>Drosophila<\/em><\/a>.\u201d<\/p>\n<p>The researchers focused on Diptericin (Dpt), a small antimicrobial peptide that mainly defends <em>Drosophila<\/em> against Gram-negative bacteria. The team examined how Diptericins function in <em>Drosophila<\/em> and evolve in response to their microbial environment.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Antimicrobial peptides (AMPs)\u2014small peptides that protect against microbial infection\u2014are crucial immune effectors in both plants and animals. They not only fight against potential infections, they also influence the composition of the host\u2019s microbiome. Little is known about the driving forces behind AMPs\u2019 rapid evolution. Now, a study uncovers the selective pressures driving the evolution of [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[385],"tags":[],"class_list":["post-168427","post","type-post","status-publish","format-standard","hentry","category-evolution"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/168427","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=168427"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/168427\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=168427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=168427"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=168427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}