{"id":16802,"date":"2015-09-01T14:47:21","date_gmt":"2015-09-01T21:47:21","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2015\/09\/dna-guided-3-d-printing-of-human-tissue-is-unveiled"},"modified":"2017-06-04T20:24:29","modified_gmt":"2017-06-05T03:24:29","slug":"dna-guided-3-d-printing-of-human-tissue-is-unveiled","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2015\/09\/dna-guided-3-d-printing-of-human-tissue-is-unveiled","title":{"rendered":"DNA-guided 3-D printing of human tissue is unveiled"},"content":{"rendered":"<p><a class=\\'blog-photo\\' href=\"https:\/\/lifeboat.com\/blog.images\/dna-guided-3-d-printing-of-human-tissue-is-unveiled.jpg\"><\/a><\/p>\n<p>A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer. They could be used for therapeutic drug screening and to help teach researchers how to grow whole human organs.<\/p>\n<p>The new technique \u2014 called DNA Programmed Assembly of Cells (DPAC) and reported in the journal <em>Nature Methods<\/em> on August 31, 2015 \u2014 allows researchers to create arrays of thousands of custom-designed organoids, such as models of human mammary glands containing several hundred cells each, which can be built in a matter of hours.<\/p>\n<p>There are few limits to the tissues this technology can mimic, said Zev Gartner, PhD, the paper\u2019s senior author and an associate professor of pharmaceutical chemistry at UCSF. \u201cWe can take any cell type we want and program just where it goes. We can precisely control who\u2019s talking to whom and who\u2019s touching whom at the earliest stages. The cells then follow these initially programmed spatial cues to interact, move around, and develop into tissues over time.\u201d<\/p>\n<p><a href=\"http:\/\/www.sciencedaily.com\/releases\/2015\/08\/150831112619.htm\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or [\u2026]<\/p>\n","protected":false},"author":367,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1489,11,19],"tags":[],"class_list":["post-16802","post","type-post","status-publish","format-standard","hentry","category-3d-printing","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/16802","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/367"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=16802"}],"version-history":[{"count":3,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/16802\/revisions"}],"predecessor-version":[{"id":69644,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/16802\/revisions\/69644"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=16802"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=16802"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=16802"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}