{"id":167771,"date":"2023-07-18T22:24:51","date_gmt":"2023-07-19T03:24:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/07\/study-sheds-light-on-mechanisms-underlying-h-pylori-induced-gastric-cancer"},"modified":"2023-07-18T22:24:51","modified_gmt":"2023-07-19T03:24:51","slug":"study-sheds-light-on-mechanisms-underlying-h-pylori-induced-gastric-cancer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/07\/study-sheds-light-on-mechanisms-underlying-h-pylori-induced-gastric-cancer","title":{"rendered":"Study sheds light on mechanisms underlying H. pylori-induced gastric cancer"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/study-sheds-light-on-mechanisms-underlying-h-pylori-induced-gastric-cancer2.jpg\"><\/a><\/p>\n<p>Helicobacter pylori (H. pylori) infections are commonly associated with abdominal pain, bloating, and acidity. Clinical evidence suggests that infection with H. pylori cagA<sup>+<\/sup> strains dramatically increases the risk of developing gastric cancer.<\/p>\n<p>A specialized protein delivered by H. pylori to the host, oncoprotein \u201cCagA,\u201d has been shown to interact with multiple host proteins and promote gastric carcinogenesis (transformation of normal cells to <a href=\"https:\/\/medicalxpress.com\/tags\/cancer+cells\/\" rel=\"tag\" class=\"\">cancer cells<\/a>). However, the underlying mechanisms associated with its biochemical activity have not been fully determined yet.<\/p>\n<p>A new study published in <i>Science Signaling<\/i> on 18 July insights into the additional mechanism of oncogenic CagA action.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Helicobacter pylori (H. pylori) infections are commonly associated with abdominal pain, bloating, and acidity. Clinical evidence suggests that infection with H. pylori cagA+ strains dramatically increases the risk of developing gastric cancer. A specialized protein delivered by H. pylori to the host, oncoprotein \u201cCagA,\u201d has been shown to interact with multiple host proteins and promote [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19],"tags":[],"class_list":["post-167771","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/167771","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=167771"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/167771\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=167771"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=167771"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=167771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}