{"id":167415,"date":"2023-07-13T06:22:21","date_gmt":"2023-07-13T11:22:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/07\/dna-element-with-a-murky-past-is-borrowing-cells-repair-machinery"},"modified":"2023-07-13T06:22:21","modified_gmt":"2023-07-13T11:22:21","slug":"dna-element-with-a-murky-past-is-borrowing-cells-repair-machinery","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/07\/dna-element-with-a-murky-past-is-borrowing-cells-repair-machinery","title":{"rendered":"DNA element with a murky past is borrowing cell\u2019s repair machinery"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dna-element-with-a-murky-past-is-borrowing-cells-repair-machinery.jpg\"><\/a><\/p>\n<p>Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell\u2019s own machinery to achieve its goals.<\/p>\n<p>In a new work appearing online Wednesday in the journal <i>Nature<\/i>, a Duke University team has determined that retrotransposons hijack a little-known piece of the cell\u2019s DNA repair function to close themselves into a ring-like shape and then create a matching double strand.<\/p>\n<p>The finding upends 40 years of conventional wisdom saying these rings were just a useless by-product of bad gene copying. It may also offer new insights into cancer, viral infections and immune responses.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell\u2019s own machinery to achieve its goals. In a new work appearing online Wednesday in the journal Nature, a Duke University team has determined that retrotransposons hijack a little-known piece of the cell\u2019s DNA repair function to close [\u2026]<\/p>\n","protected":false},"author":367,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-167415","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/167415","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/367"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=167415"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/167415\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=167415"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=167415"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=167415"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}