{"id":166571,"date":"2023-06-28T02:22:51","date_gmt":"2023-06-28T07:22:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/06\/mitochondrial-research-rewrites-understanding-of-parkinsons-disease-pathway"},"modified":"2023-06-28T02:22:51","modified_gmt":"2023-06-28T07:22:51","slug":"mitochondrial-research-rewrites-understanding-of-parkinsons-disease-pathway","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/06\/mitochondrial-research-rewrites-understanding-of-parkinsons-disease-pathway","title":{"rendered":"Mitochondrial research rewrites understanding of Parkinson\u2019s disease pathway"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mitochondrial-research-rewrites-understanding-of-parkinsons-disease-pathway2.jpg\"><\/a><\/p>\n<p>While mitochondria play a crucial role in producing the energy our cells need to carry out their various functions, when damaged, they can have profound effects on cellular function and contribute to the development of various diseases.<\/p>\n<p>Broken-down <a href=\"https:\/\/medicalxpress.com\/tags\/mitochondria\/\" rel=\"tag\" class=\"\">mitochondria<\/a> are usually removed and recycled through a garbage disposal process known as \u201cmitophagy.\u201d<\/p>\n<p>PINK1 and Parkin are two proteins vital to this process, responsible for \u201ctagging\u201d malfunctioning mitochondria for destruction. In Parkinson\u2019s disease, mutations in these proteins can result in the accumulation of damaged mitochondria in the brain, which can lead to motor symptoms such as tremors, stiffness and difficulty with movement.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>While mitochondria play a crucial role in producing the energy our cells need to carry out their various functions, when damaged, they can have profound effects on cellular function and contribute to the development of various diseases. Broken-down mitochondria are usually removed and recycled through a garbage disposal process known as \u201cmitophagy.\u201d PINK1 and Parkin [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-166571","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/166571","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=166571"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/166571\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=166571"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=166571"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=166571"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}