{"id":165536,"date":"2023-06-11T00:26:02","date_gmt":"2023-06-11T05:26:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/06\/researchers-advance-dna-nanostructure-stability"},"modified":"2023-06-11T00:26:02","modified_gmt":"2023-06-11T05:26:02","slug":"researchers-advance-dna-nanostructure-stability","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/06\/researchers-advance-dna-nanostructure-stability","title":{"rendered":"Researchers advance DNA nanostructure stability"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researchers-advance-dna-nanostructure-stability3.jpg\"><\/a><\/p>\n<p>Researchers at the University at Albany\u2019s RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium. The method improves the biostability of the structures, making them more useful and reliable in a range of applications. The work appears in the journal <i>Small<\/i> this month.<\/p>\n<p>When we think of DNA, the first association that comes to mind is likely genetics\u2014the <a href=\"https:\/\/phys.org\/tags\/double+helix+structure\/\" rel=\"tag\" class=\"\">double helix structure<\/a> within cells that houses an organism\u2019s blueprint for growth and reproduction. A rapidly evolving area of DNA research is that of DNA nanostructures\u2014synthetic molecules made up of the same <a href=\"https:\/\/phys.org\/tags\/building+blocks\/\" rel=\"tag\" class=\"\">building blocks<\/a> as the DNA found in living cells, which are being engineered to solve critical challenges in applications ranging from medical diagnostics and <a href=\"https:\/\/phys.org\/tags\/drug\/\" rel=\"tag\" class=\"\">drug<\/a> delivery to materials science and data storage.<\/p>\n<p>\u201cIn this work, we assembled DNA nanostructures without using magnesium, which is typically used in this process but comes with challenges that ultimately reduce the utility of the nanostructures that are produced,\u201d said Arun Richard Chandrasekaran, corresponding author of the study and senior research scientist at the RNA Institute.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the University at Albany\u2019s RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium. The method improves the biostability of the structures, making them more useful and reliable in a range of applications. The work appears in the journal Small this month. When we think of DNA, [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,1523,412,4],"tags":[],"class_list":["post-165536","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-computing","category-genetics","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/165536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=165536"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/165536\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=165536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=165536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=165536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}