{"id":164157,"date":"2023-05-19T00:24:24","date_gmt":"2023-05-19T05:24:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/05\/forgotten-antibiotic-from-decades-ago-could-be-a-superbug-killer"},"modified":"2023-05-19T00:24:24","modified_gmt":"2023-05-19T05:24:24","slug":"forgotten-antibiotic-from-decades-ago-could-be-a-superbug-killer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/05\/forgotten-antibiotic-from-decades-ago-could-be-a-superbug-killer","title":{"rendered":"Forgotten Antibiotic From Decades Ago Could Be a Superbug Killer"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/forgotten-antibiotic-from-decades-ago-could-be-a-superbug-killer2.jpg\"><\/a><\/p>\n<p>An antibiotic developed some 80 years ago before being abandoned and forgotten could again offer exciting new solutions, this time to the <a href=\"https:\/\/www.sciencealert.com\/nightmare-drug-resistant-superbugs-are-causing-more-deaths-than-previously-estimated\">emerging threat<\/a> of drug-resistant superbugs.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2095086\/\">Half of the bacteria-killing drugs we use today<\/a> are variations of compounds that were found nearly a century ago, during this \u2018golden age\u2019 of antibiotics. One called streptothricin was <a href=\"https:\/\/journals.sagepub.com\/doi\/abs\/10.3181\/00379727-49-13515\">isolated<\/a> in the 1940s, drawing attention for its potential in treating infections caused by what are known as gram-negative bacteria.<\/p>\n<p>Unlike gram-positive bacteria, these microbes lack a robust cell wall that many antibiotics target. <a href=\"https:\/\/www.sciencealert.com\/arylomycin-analogue-gram-negative-antibiotic-first-in-50-years\">Finding alternatives<\/a> has been one of the big challenges for the pharmaceutical industry. In 2017, the <a href=\"https:\/\/www.sciencealert.com\/what-does-the-world-health-organisation-do\" class=\"\" rel=\"nofollow\" target=\"_self\">World Health Organization<\/a> (WHO) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7144564\/\">released<\/a> a list of the most dangerous, drug-resistant pathogens out there. Most were gram-negative bacteria.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An antibiotic developed some 80 years ago before being abandoned and forgotten could again offer exciting new solutions, this time to the emerging threat of drug-resistant superbugs. Half of the bacteria-killing drugs we use today are variations of compounds that were found nearly a century ago, during this \u2018golden age\u2019 of antibiotics. One called streptothricin [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-164157","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/164157","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=164157"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/164157\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=164157"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=164157"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=164157"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}