{"id":162166,"date":"2023-04-14T10:31:18","date_gmt":"2023-04-14T15:31:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/04\/crispr-breakthrough-scientists-can-now-turn-genes-on-and-off-at-whim"},"modified":"2023-04-14T10:31:18","modified_gmt":"2023-04-14T15:31:18","slug":"crispr-breakthrough-scientists-can-now-turn-genes-on-and-off-at-whim","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/04\/crispr-breakthrough-scientists-can-now-turn-genes-on-and-off-at-whim","title":{"rendered":"CRISPR Breakthrough: Scientists Can Now Turn Genes On and Off at Whim"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/crispr-breakthrough-scientists-can-now-turn-genes-on-and-off-at-whim2.jpg\"><\/a><\/p>\n<p>The gene-editing system CRISPR-Cas9 which has revolutionized genetic engineering over the past decade involves cutting DNA strands which is a process that can be quite hard to control and can result in unwanted genetic changes. Now, thanks to researchers at the Massachusetts Institute of Technology and the University of California, San Francisco (UCSF), a new gene-editing technology called CRISPRoff can change that, according to a press release.<\/p>\n<p>\u201cFast forward four years [from the initial grant], and CRISPRoff finally works as envisioned in a science fiction way,\u201d says co-senior author Luke Gilbert. \u201cIt\u2019s exciting to see it work so well in practice.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The gene-editing system CRISPR-Cas9 which has revolutionized genetic engineering over the past decade involves cutting DNA strands which is a process that can be quite hard to control and can result in unwanted genetic changes. Now, thanks to researchers at the Massachusetts Institute of Technology and the University of California, San Francisco (UCSF), a new [\u2026]<\/p>\n","protected":false},"author":413,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-162166","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/162166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/413"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=162166"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/162166\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=162166"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=162166"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=162166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}