{"id":159671,"date":"2023-03-06T19:25:26","date_gmt":"2023-03-07T01:25:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/03\/anti-aging-supplements-science-snake-oil-and-how-do-we-know"},"modified":"2023-03-06T19:25:26","modified_gmt":"2023-03-07T01:25:26","slug":"anti-aging-supplements-science-snake-oil-and-how-do-we-know","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/03\/anti-aging-supplements-science-snake-oil-and-how-do-we-know","title":{"rendered":"Anti-aging Supplements: Science, Snake Oil, and How Do We Know?"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/dJwQ3rMs2Dg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>\ud83c\uddec\ud83c\udde7FREE WEBINAR\ud83c\uddee\ud83c\uddf9: <a href=\"https:\/\/draronica.com\/free-webinar\/\">https:\/\/draronica.com\/free-webinar\/<\/a><\/p>\n<p>In this Ask Me Anything interview, Prof. Matt Kaeberlein discusses the evidence (and lack thereof) behind popular anti-aging supplements and interventions. Starting from his current research on rapamycin for healthy longevity in dogs (The Dog Aging Project), he describes the promises and perils of anti-aging medicine and shares with us some tips on how to become better critical thinkers and protect us from hype and snake oil.<\/p>\n<p>This interview is a must watch for everyone who wants to develop a critical stance toward the field of longevity research and balance enthusiasm with evidence.<\/p>\n<p>I hope you enjoy this interview!<\/p>\n<p>TIMESTAMPS<br \/> 00:00 Introduction.<br \/> 04:33 Definitions: Aging, lifespan, healthspan.<br \/> 09:08 What is biohacking.<br \/> 14:56 The Dog Aging project.<br \/> 19:39 Rapamycin: Longevity effects in mice.<br \/> 22:28 Can rapamycin impair muscle growth? Is it in contraindicated for people who want to build muscle mass?<br \/> 27:09 Exercise, inhibition of mTor, and rationale for cycling rapamycin and exercise.<br \/> 29:46 Getting around the growth vs. resilience tradeoff in longevity.<br \/> 32:00 Epigenetic clocks: Hope vs. hype.<br \/> 32:43 Best functional markers of longevity.<br \/> 36:30 Sterile inflammation, auto-immunity, and immune senescence.<br \/> 40:24 The best and worst longevity supplements for Matt Kaeberlein.<br \/> 45:50 What longevity hacks Matt implements in his own life.<br \/> 48:00 Lucia\u2019s and Matt\u2019s thoughts on calorie restriction for longevity.<br \/> 50:30 How can people discriminate between science and sneak oil?<\/p>\n<p>\ud83d\udc36 The Dog Aging project: <a href=\"https:\/\/dogagingproject.org\/\">https:\/\/dogagingproject.org\/<\/a><\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2023\/03\/anti-aging-supplements-science-snake-oil-and-how-do-we-know\">Continue reading \u201cAnti-aging Supplements: Science, Snake Oil, and How Do We Know?\u201d | &gt;<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\ud83c\uddec\ud83c\udde7FREE WEBINAR\ud83c\uddee\ud83c\uddf9: https:\/\/draronica.com\/free-webinar\/ In this Ask Me Anything interview, Prof. Matt Kaeberlein discusses the evidence (and lack thereof) behind popular anti-aging supplements and interventions. Starting from his current research on rapamycin for healthy longevity in dogs (The Dog Aging Project), he describes the promises and perils of anti-aging medicine and shares with us some tips [\u2026]<\/p>\n","protected":false},"author":530,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412,269,224],"tags":[],"class_list":["post-159671","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics","category-life-extension","category-science"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/530"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=159671"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159671\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=159671"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=159671"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=159671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}